London based
Competitive Salary + Excellent Benefits
Do you have Bioinformatics experience from within Clinical Diagnostics?
Would you like to work for a leading developer of NGS based clinical diagnostics?
My client, the inventors of semiconductor-based next-generation sequencing (NGS) technology, are developing a revolutionary new NGS-based diagnostic platform in an easy-to-use, cartridge-based system designed to generate a clinically actionable result direct from clinical specimen, in a matter of hours. They are currently looking to hire outstanding scientific talent to join the multi-disciplinary NGS platform development team, filling key roles in the rapidly expanding program. The team is entirely engaged in developing the company's revolutionary NGS products for point-of-need diagnostic applications. This involves a multidisciplinary mixture of electrical engineering, molecular biology, chemistry, mechanical design, software, bioinformatics and product design.
Their technology uses targeted sequencing to provide rapid and high-quality diagnostic information in a wide variety of clinical settings that include pathogen detection and oncology. Bioinformatics capacity will be a key component in achieving this goal, with the Senior Bioinformatician playing a key role in this development.
Person Specification
We are looking for a talented Senior Bioinformatician, who can contribute to the development of bioinformatics software to analyse and report out clinically-relevant results generated by the sequencing platform, as well as to assist in the identification of medically relevant targets and in the design of sequencing assays for our patented sequencing technology.You'll need passion, drive and enthusiasm for your work; who wants their innovation and hard work to affect a paradigm shift in clinical care. Someone who strives for exceptional results and who can deliver pragmatic solutions on time.
You will have the capability to work collaboratively within the company and their external partners, listening, discussing, understanding, advising and ultimately contributing to delivery of a bioinformatics pipeline that will enable efficient clinical NGS to become a healthcare standard.
Key Responsibilities will include;
- Design, implement, validate and maintain world-class Biostatistics tools to demonstrate
capability of our BioInformatics processes as well as Clinical products performance. - Actively contribute to the development of the bioinformatics pipeline component of
targeted sequencing solution. - Train Internal users in BioStatistics methodologies to guarantee statistical power of In silico and In vitro experiments.
- Actively promote scientific interactions within the BioInformatics team by setting-up technical reviews and brainstorming sessions to answer internal user's needs.
- Participate in relevant regulatory forums to help ensure our product
designs reflect the Bioinformatics challenges of a regulated diagnostic sample-to-answer sequencing tests.
Qualifications & Experience Required:
- Experience of sequence Bioinformatics and the use of databases for clinical applications.
- Strong academic background in bioinformatics and biostatistics
- Proven successful experience as Biostatistician in a Clinical Diagnostics company
- Deep knowledge of Mathematics applied to product development (DOE, performance analysis, Descriptive statistics, Parametric and non-parametric tests, sampling).
- Knowledge of the Quality and Regulatory requirements for the design and development of IVD assays.
- Demonstrate a strong discipline for thorough documentation
Experience of statistical analysis software using R, knowledge of the publicly available SNP databanks and of scripting languages such as Python, Perl and/or Bash would be an advantage.
Knowledge in biomarker discovery (expression signatures) in oncology and of Bayesian statistics would be an advantage.
Please apply online or call Neil Walton on 02030964706
The recruiter has stated that all applicants for this job should be able to prove they are legally entitled to work in the UK. SRG is a trading name of Science Recruitment Group Ltd an Employment Business/Agency.